Description
MOTS-c Research Kit (x5)
Bulk research pack of MOTS-c (Mitochondrial ORF of the 12S rRNA-c), a 16-amino-acid peptide encoded in mitochondrial DNA. This kit contains 5 × 10 mg vials (50 mg total) — approximately a 30-day research-reference supply at 5 mg every 3rd day. For the single-vial monograph see MOTS-c.
Mechanism of Action (Research Context)
MOTS-c is a mitochondrial-derived peptide (MDP) that research describes as activating AMPK signaling, improving insulin sensitivity, and regulating metabolic homeostasis (Lee et al., Cell Metab, 2015).
Compound Properties (per vial)
- Compound: MOTS-c (16-aa mitochondrial-derived peptide)
- Molecular Weight: ~2174.5 g/mol
- Kit Contents: 5 × 10 mg vials (50 mg total)
- Purity: ≥98% (HPLC)
Research-Reference Dosing
Published protocols are primarily preclinical. Research-reference human protocols have referenced ~5 mg every 3rd day as a reference cadence. The 50 mg total kit is consistent with ~30 days at this interval.
What the Kit Includes
- Lyophilized peptide vials (see quantities below)
- Syringes (insulin-gauge)
- Alcohol prep pads
- Reconstitution solution
- Mixing syringe
Add $15 if you want us to reconstitute your vials before shipping.
Research Findings
- Lee et al. (Cell Metab, 2015) showed AMPK activation, improved glucose homeostasis, and reduced diet-induced obesity in mice.
- Plasma MOTS-c levels decline with aging in human cohort studies, associated with metabolic decline.
- Published human efficacy data is limited — most findings come from preclinical/animal studies.
Known Side Effects
- No human clinical safety database is available in peer-reviewed literature.
- Injection-site reactions typical of short peptides may occur.
Storage & Handling
- Unopened lyophilized vials: refrigerate at 2-8 °C; long-term storage at −20 °C recommended. Protect from light.
- After reconstitution: refrigerate at 2-8 °C and use within 14-28 days per standard peptide stability guidance.
- Avoid repeated freeze-thaw cycles of reconstituted material.
Shipping
UPS 2-Day shipping: $7 Texas / $12 out of state / $35 for ICE (insulated cold pack).
Certificate of Analysis
Third-party HPLC and mass-spectrometry certificates are available on request. Contact us with your order number for the COA matching your kit.
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