Vilon (20mg)

Description

What is Vilon?

Vilon (Lys‑Glu / KE) is a synthetic dipeptide from the Khavinson series of “peptide bioregulators” developed at the St. Petersburg Institute of Bioregulation and Gerontology. It is the short synthetic analog of the larger thymus‑derived bioregulator Thymalin. The Russian literature claims immunomodulatory, geroprotective, and anti‑tumor activity, with data largely confined to Russian‑language publications and small institutional cohorts.

Mechanism of Action

• Proposed epigenetic modulation via direct DNA binding in promoter regions (Khavinson model)
• Claimed restoration of T‑cell function and cytokine balance in aged animals
• Reported increase in telomere length and cell‑doubling capacity in fibroblast culture (Khavinson data)
• Antioxidant effects in preclinical models

Compound Properties

• Sequence: Lys‑Glu (KE)
• Molecular formula: C₁₁H₂₁N₃O₅
• Molecular weight: ~275.3 g/mol
• Form: Lyophilized powder
• Unit size: 20 mg / vial
• Source: Solid‑phase peptide synthesis; ≥98% purity by HPLC

Research‑Reference Dosing

Published research‑reference ranges:

• Khavinson & Malinin, Gerontological Aspects of Peptide Regulation of Body Function (2006 monograph): immunomodulatory and geroprotective data.
• Anisimov et al., Biogerontology and Neuroendocrinology Letters: rodent lifespan and tumor‑incidence studies with Khavinson peptides.
• Peer‑reviewed Western‑journal replication is very limited.

Research Findings

• Claimed lifespan extension and reduced spontaneous tumor incidence in aged rodents (Khavinson/Anisimov)
• Restored T‑lymphocyte counts and function in aged animals
• Evidence base is Russian‑dominated and has not been rigorously replicated in independent Western laboratories

Known Side Effects Reported in Research/Trials

• Generally well tolerated in published cohorts
• Rare injection‑site reactions
• No characteristic adverse event pattern
• Long‑term human safety data is limited

Storage & Handling

• Lyophilized (unreconstituted) vials: store at −20°C long‑term; short‑term 2–8°C acceptable.
• After reconstitution with bacteriostatic or sterile water: store at 2–8°C; use within 14–28 days per standard peptide stability guidance.
• Protect from light, heat, and repeated freeze‑thaw cycles. Handle in a sterile laboratory environment.

Certificate of Analysis

A Certificate of Analysis (COA) confirming identity and purity by HPLC / MS is available upon request. Contact Lonestar Peptides for lot‑specific documentation.

Summaries reference peer‑reviewed preclinical and clinical literature available as of early 2025. Newer findings may not be reflected. Researchers should consult current literature and conduct their own due diligence. Lonestar Peptides makes no claim of therapeutic benefit.